PT-141

PT-141 (bremelanotide) is an FDA-approved peptide therapy developed from the melanocortin system, derived originally from Melanotan II. During early Melanotan I...

FDA-approved (Vyleesi) for HSDD in premenopausal women (2019). Ongoing off-label

Melanotan II

Melanotan II is a synthetic cyclic heptapeptide analog of alpha-melanocyte stimulating hormone (α-MSH). Originally developed at the University of Arizona as a s...

Not FDA-approved. Considered an illicit substance in many jurisdictions. Safety

Kisspeptin

Kisspeptin refers to a family of peptides (KP-54, KP-14, KP-13, KP-10) encoded by the KISS1 gene, which are essential regulators of the hypothalamic-pituitary-g...

Active Phase II clinical trials for infertility and reproductive disorders. A sy

Kisspeptin-10

Kisspeptin-10 (KP-10) is the shortest biologically active form of kisspeptin, corresponding to the last 10 amino acids of the KISS1 gene product. While less pot...

Clinical research ongoing. Studies exploring fertility applications, sexual dysf

Oxytocin

Oxytocin is a 9-amino acid cyclic neuropeptide synthesized in the hypothalamus and released from the posterior pituitary. Colloquially known as the 'love hormon...

FDA-approved for obstetric use (Pitocin). Intranasal form under active Phase II/

Leuprolide

Leuprolide is a synthetic nonapeptide analog of gonadotropin-releasing hormone (GnRH) with approximately 80-fold greater potency than the natural hormone. Parad...

FDA-approved for multiple indications since 1985. Extensively used worldwide. Ro

Gonadorelin (GnRH)

Gonadorelin is the synthetic form of naturally occurring gonadotropin-releasing hormone (GnRH/LHRH), a decapeptide produced by hypothalamic neurons and released...

FDA-approved for diagnostic use (Factrel). Pulsatile pump therapy approved in Eu