Immune Support
Peptides that modulate T-cell activity, cytokine production, and innate or adaptive immunity.
15 peptides in this category
Thymosin Alpha-1
Thymosin Alpha-1 (Tα1) is a 28-amino acid peptide naturally secreted by the thymus gland that plays a central role in T-cell maturation, differentiation, and im...
Approved drug (Zadaxin/Thymalfasin) in many countries. Ongoing Phase III trialsVilon
Vilon is a synthetic dipeptide (Lys-Glu) bioregulator developed by Professor Vladimir Khavinson from amino acid analysis of Thymalin, a natural thymus extract w...
Russian preclinical and limited clinical research. Part of the Khavinson peptideLL-37
LL-37 is a 37-amino acid cationic antimicrobial peptide (AMP), the only known member of the cathelicidin family in humans. It is generated by proteolytic cleava...
Extensive preclinical research. Some clinical exploration for wound healing andThymulin
Thymulin (facteur thymique sérique, FTS) is a nonapeptide hormone produced exclusively by thymic epithelial cells, characterized by its unique zinc-binding requ...
Russian and European preclinical research. Phase I/II explored in various immuneVasoactive Intestinal Peptide
Vasoactive Intestinal Peptide (VIP) is a naturally occurring 28-amino acid neuropeptide found in the nervous system and immune cells throughout the body. It act...
Extensive preclinical data. Limited clinical trials for inflammatory conditions.KPV
KPV (Lys-Pro-Val) is the C-terminal active tripeptide fragment of alpha-melanocyte stimulating hormone (α-MSH). It retains the anti-inflammatory and cytoprotect...
Preclinical data primarily. Research phase for IBD and wound healing. No FDA-appThymogen
Thymogen is a synthetic dipeptide (Glu-Trp) bioregulator derived from the thymus and representing another member of the Khavinson peptide family. It combines gl...
Russian preclinical and clinical research. Khavinson peptide bioregulator group.KPV
KPV is a tripeptide (Lys-Pro-Val) representing the C-terminal three amino acids of alpha-melanocyte stimulating hormone (α-MSH). It retains the anti-inflammator...
Preclinical. Colitis animal models show oral nanoparticle efficacy. No human triLeuprolide
Leuprolide is a synthetic nonapeptide analog of gonadotropin-releasing hormone (GnRH) with approximately 80-fold greater potency than the natural hormone. Parad...
FDA-approved for multiple indications since 1985. Extensively used worldwide. RoDefensin HNP-1
HNP-1 (Human Neutrophil Peptide-1) is a 30-amino acid cationic alpha-defensin stored in the azurophilic granules of human neutrophils and released during phagoc...
Extensively characterized in vitro. Used as research tool for antimicrobial peptThymalfasin (Thymosin Alpha-1 Clinical)
Thymalfasin is the pharmaceutical-grade, synthetic form of thymosin alpha-1 (Tα1), marketed under the brand name Zadaxin. It is approved in over 37 countries fo...
Approved in 37+ countries. Extensive phase III data for hepatitis B/C. COVID-19Thymosin Beta-4 Fragment (Ac-SDKP)
Ac-SDKP (N-acetyl-seryl-aspartyl-lysyl-proline) is a naturally occurring tetrapeptide released from thymosin beta-4 by prolyl oligopeptidase and ACE2 cleavage. ...
Preclinical and Phase I/II clinical data for myeloprotection. Antifibrotic effecInterferon-Tau
Interferon-tau (IFN-τ) is a unique type I interferon produced by the trophoblast cells of ruminants during early pregnancy. Unlike other type I interferons (α, ...
Phase I/II clinical trials for MS and autoimmune diseases. Not FDA-approved. ComThymosin Beta-4 Sulfoxide (TB4-SO)
Thymosin beta-4 sulfoxide (TB4-SO) is the naturally occurring oxidized form of Thymosin Beta-4 generated by methionine-6 oxidation. Unlike the reduced parent co...
Preclinical. Research tool defining TB4 oxidation product biology. Not developedEnfuvirtide (T-20)
Enfuvirtide (Fuzeon) is a synthetic 36-amino acid peptide HIV fusion inhibitor that was the first member of this antiretroviral drug class and remains the only ...
FDA-approved 2003. Standard of care for multidrug-resistant HIV. High injection