Muscle Growth Peptides — Research Database

TB-500

TB-500 is a synthetic heptapeptide corresponding to the N-acetylated active fragment (amino acids 17–23) of the endogenous 43-amino acid signaling protein thymo...

Extensive animal model data. TB-500 is classified as a prohibited substance by W

CJC-1295

CJC-1295 is a 29-amino acid synthetic analog of growth hormone-releasing hormone (GHRH), structurally based on the first 29 amino acids of native GHRH with four...

Preclinical and Phase I/II human trials completed demonstrating GH/IGF-1 elevati

Ipamorelin

Ipamorelin is a selective synthetic pentapeptide growth hormone secretagogue, developed as part of a major chemistry program targeting GHRP analogs. Unlike olde...

Well-characterized in preclinical and early clinical studies. Not FDA-approved a

GHRP-6

GHRP-6 was one of the first synthetic growth hormone secretagogues discovered, derived from the structure of the endogenous opioid peptide met-enkephalin. It is...

Well-established in preclinical research. Not FDA-approved. Widely used as a res

GHRP-2

GHRP-2 is a synthetic hexapeptide derived from met-enkephalin structure that functions as a potent GHS-R1a agonist. It is one of the most potent GHRPs in terms ...

Clinical trials completed for diagnostic use (approved in Japan as Pralmorelin).

Follistatin-344

Follistatin-344 is a 344-amino acid isoform of the native glycoprotein follistatin, engineered for targeted research applications. Follistatin is a potent endog...

Active clinical trials as gene therapy (AAV1-FS344) for neuromuscular diseases i

IGF-1 LR3

IGF-1 LR3 (Long R3 IGF-1) is a synthetic 83-amino acid analog of human IGF-1, engineered with two modifications: a 13-amino acid N-terminal extension and a glut...

Widely used as a research tool in muscle biology. Not FDA-approved. Banned by WA

MGF

Mechano Growth Factor (MGF) is a splice variant of IGF-1 (the IGF-1Ec isoform in humans, IGF-1Eb in rodents) produced in skeletal muscle in response to mechanic...

Research tool used extensively in muscle biology. PEG-MGF adds stability for in

ACE-031

ACE-031 is a fusion protein consisting of the extracellular domain of activin receptor type IIB (ActRIIB) fused to the Fc region of human IgG1. By acting as a '...

Clinical development discontinued in 2013 after Phase II halt due to telangiecta

MK-677 (Ibutamoren)

MK-677 (ibutamoren) is a potent, orally active, non-peptide GHS-R1a (ghrelin receptor) agonist that mimics ghrelin to stimulate pulsatile growth hormone secreti...

Multiple Phase II clinical trials completed. Not FDA-approved as a prescription

Carnosine

Carnosine is an endogenous dipeptide (β-alanyl-L-histidine) found in high concentrations in skeletal muscle, cardiac muscle, and neuronal tissue. It is a multif...

Extensively studied in vitro and animal models. Human studies for exercise perfo

BPC-157 + TB-500 Stack

The BPC-157 + TB-500 combination, sometimes called the 'Wolverine Stack,' is one of the most studied and widely referenced peptide synergy protocols in the rese...

Each compound individually: preclinical (rodent studies). Combination: primarily

Insulin-Like Growth Factor 1 (IGF-1)

Insulin-Like Growth Factor 1 (IGF-1) is a 70-amino acid single-chain growth factor structurally homologous to insulin, primarily synthesized in the liver in res...

Native IGF-1: well characterized; diagnostic biomarker for GH disorders. Mecaser

Ostarine (MK-2866)

Ostarine (MK-2866, Enobosarm) is one of the most extensively studied Selective Androgen Receptor Modulators (SARMs). Developed by GTx Inc. (now Onconova) and Me...

Phase II and Phase III clinical trials completed for cancer cachexia and stress

RAD-140 (Testolone)

RAD-140 (Testolone) is a potent, orally bioavailable nonsteroidal SARM developed by Radius Health. It demonstrates one of the highest anabolic-to-androgenic rat...

Phase I clinical trials ongoing for breast cancer. Preclinical data in primates

Muscle Growth